Threeweeksagoa60-year-oldwomanhadsuddenlossofconsciousness.
A
B
C
Whatisyourdiagnosis?
TheanswerisAtypicalMeningioma
Braininvasionisoneofthemajorthreecriteriathatformulatesthediagnosisofanatypicalmeningioma,evenwhenotherpathologicalfindingsarebenign.
Thecaseshowsasmallpartoftumorthatinvadesthebrainparenchyma(arrow,a),afindingfurtherbeingvalidatedbyaseparatepathologicalspecimenfromthisregionshowinginvasionoftheunderlyingbrainparenchyma(b)bythebenign-lookingmeningioma.
Sectionsofthemaintumormassrevealedamixedpatternofbenignmeningothelialandfibrousmeningioma.
Nolossofarchitecture,increaseinmitoticactivity,ornecrosiswasidentified.
TheMIB-1labelingindexwas2.
Brainparenchymainvasionandleptomeningealdestructionmightexplainthecausesofperitumoralbrainedema(arrow,c).
中文版:
女性,60岁,3周前突发意识丧失
诊断:非典型脑膜瘤
脑组织侵犯是诊断非典型脑膜瘤的三个主要标准之一,尽管病理学表现为良性。
该病例中可见局部肿瘤组织侵犯脑实质(A图箭头),该部分肿瘤组织被病理学证实为具有良性特征的脑膜瘤侵犯潜在的脑组织(B图)。
肿瘤切片显示为良性、脑膜上皮和纤维性混合型脑膜瘤。
未发现组织结构丢失、有丝分裂增强以及坏死。
MIB-1标记指数为2.
脑组织侵犯和软脑膜破坏可能是引起瘤周水肿的原因(C图箭头)。
FromAJNRClassicCase
治疗皮肤病最好医院在哪里白斑病转载请注明:http://www.tzdgt.com/dynmlyh/3763.html